Literatuur

Uitgebreid Klinisch Studieprogramma

7 published pharmacokinetic studies

• Darwish M et al. Clin Ther 2006;28:715–725
• Darwish M et al. Clin Pharmacokinet 2005;44:1279–1286
• Darwish M et al. Clin Pharmacokinet 2006;45:843–850
• Darwish M et al. Clin Ther 2006;28:707–714
• Darwish M et al. Clin Method 2007;47:1–8
• Darwish M et al. J Clin Pharmacol 2007;47:343–350
• Darwish M et al. Clin Drug Invest 2007;27:605–611

3 published phase III clinical trials (efficacy and safety)

• Portenoy R et al. Clin J Pain 2006;22:805–811
• Slatkin N et al. J Support Oncol 2007;15:327–334
• Ashburn et al. Anesth Analg 2011;112:693–702

1 long-term safety study

• Weinstein SM et al. Cancer 2009;115:2571–2579

1 phase IV clinical trial

• Davies A et al. presented at World Congress of Pain Clinicians 2012, poster 80
• Davies A et al. presented at World Congress of Pain Clinicians 2012, poster 81